Fig. 1. All nine parameters as a function of effort-reward imbalance and overcommitment. The risk scores were first standardized using normalized Z scores. The summed risk score was computed as the sum of these nine Z scores using the following formula: Z_glucose + Z_insulin + Z_TC + Z_TG + Z_fibrinogen + Z_PAI-1 + Z_{tPA antigen} - Z_{tPA activity} - Z_HDL.