Fig. 3. Survival probability in experiment 1 in (A) tumor cell–injected mice receiving chemotherapy (TC) or drug vehicle (TV) and (B) in tumor cell vehicle–injected mice receiving chemotherapy (NTC). Day 0 is the day of chemotherapy (adriamycin 4.0 mg/kg and cyclophosphamide 61.5 mg/kg) or drug vehicle initiation. The first symbol represents the time at which the first death occurred in each condition. (A) For TV mice, survival probability was significantly greater in IG mice than in both GI and GG mice (
2 = 12.42 and 20.18, respectively, p values < .001). As expected, TC mice (N = 9 GG, 14 GI, and 20 IG) survived significantly longer than TV mice (N = 6 GG, 8 GI, and 10 IG; 2 = 38.371, p < .001). (B) For NTC mice (N = 11 GG, 15 GI, and 20 IG), survival probability was significantly greater in GI mice than in IG mice (2 = 4.588, p < .05).