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Psychosomatic Medicine 12:73-77 (1950)
© 1950 American Psychosomatic Society

Adrenal Cortical Responsivity of Psychotic Patients in Relation to Electroshock Treatments

HUDSON HOAGLAND Ph.D.1, ENOCH CALLAWAY M.D.1, FRED ELMADJIAN Ph.D.1, and GREGORY PINCUS Sc.D.1

1 Worcester Foundation for Experimental Biology, The Worcester State Hospital and the Department of Physiology, Tufts School of Medicine

Comparisons of adrenal activation in response to 25 mg. of injected ACTH and to subconvulsive electroshock have been made in 9 schizophrenic patients using eight indices of adrenal function.

A significant positive correlation is described between adrenal cortex responsivity to pretreatment injections of ACTH and prognosis in subsequent electroshock therapy.




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