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Psychosomatic Medicine 23:420-425 (1961)
© 1961 American Psychosomatic Society

Comments on the Use of Blood Pepsin (Pepsinogen) as a Research Technique

MARTIN L. PILOT M.D.1 and HOWARD M. SPIRO M.D.1

1 Departments of Psychiatry and Medicine, Yale University School of Medicine, New Haven, Conn.

The mechanisms underlying the production of blood pepsin are presented. The use of blood pepsin in psychiatric research is reviewed and criticized. Emphasis is given to the neglect of gastric mucosal factors in the interpretation of blood pepsin changes by workers active in the field.

Submitted on September 12, 1960






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Copyright © 1961 by the American Psychosomatic Society