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Psychosomatic Medicine 25:285-291 (1963)
© 1963 American Psychosomatic Society

Duodenal Ulcer in One of Identical Twins

A Follow-up Study

MARTIN L. PILOT M.D.1, JESSE RUBIN M.D.2, ROY SCHAFER Ph.D.1, and HOWARD M. SPIRO M.D.1

1 Departments of Psychiatry and Medicine, Yale University School of Medicine, New Haven, Conn.
2 Departments of Psychiatry and Medicine, Yale University School of Medicine, New Haven, Conn.; Address as of July 1, 1963: Department of Psychiatry, Georgetown University, Washington, D.C.

A follow-up of a pair of identical twins, one of whom, John, had a duodenal ulcer for 9 years, is presented. The second twin, Fred, presumably had been shielded from the development of disease by virtue of having a more flexible, comfortable personality structure, as well as a more successful marriage, within which his wife provided for him. He developed ulcer disease when his wife lost her job in an economic recession and thought she was pregnant. John, however, seemed to be more vulnerable to the impact of the mother's death and he experienced an exacerbation at that time.

Submitted on October 29, 1962






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