Psychosomatic Medicine Faster Service from Outside North America
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by SACHAR, E. J.
Right arrow Articles by HANDLON, J. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by SACHAR, E. J.
Right arrow Articles by HANDLON, J. H.

Psychosomatic Medicine 27:435-445 (1965)
© 1965 American Psychosomatic Society

Corticosteroid Excretion in Normal Young Adults Living Under "Basal" Conditions

EDWARD J. SACHAR M.D.1, JOHN W. MASON M.D.2, JACOB R. FISHMAN M.D3, DAVID A. HAMBURG M.D.4, and JOSEPH H. HANDLON PH.D.5

1 Department of Neuroendocrinology, Walter Reed Army Institute of Research, Washington, D. C., and the Adult Psychiatry Branch, National Institute of Mental Health, Bethesda, Md.; Department of Psychiatry, Harvard Medical School, Boston, Mass.
2 Department of Neuroendocrinology, Walter Reed Army Institute of Research, Washington, D. C., and the Adult Psychiatry Branch, National Institute of Mental Health, Bethesda, Md.
3 Department of Neuroendocrinology, Walter Reed Army Institute of Research, Washington, D. C., and the Adult Psychiatry Branch, National Institute of Mental Health, Bethesda, Md.; Department of Psychiatry, Howard University College of Medicine, Washington, D. C.
4 Department of Neuroendocrinology, Walter Reed Army Institute of Research, Washington, D. C., and the Adult Psychiatry Branch, National Institute of Mental Health, Bethesda, Md.; Department of Psychiatry, Stanford University School of Medicine, Palo Alto, Cal.
5 Department of Neuroendocrinology, Walter Reed Army Institute of Research, Washington, D. C., and the Adult Psychiatry Branch, National Institute of Mental Health, Bethesda, Md.; Division of Organizational Science, Case Institute of Technology, Cleveland, Ohio.

Under basal conditions in a hospital setting, mean 17-OHCS excretion for normal 18- to 25-year-old males and females was 8.5 (13.3–5.5) and 5.1 mg./day (8.6–3.0), respectively. Weight "correction" did not abolish this significant sex difference; it did alter somewhat the rank-order of "high" to "low" 17-OHCS excretors. Values for males were about 50% higher than those reported in outpatient studies. Subjects tended to be relatively consistent in 17-OHCS excretion, although individuals varied. On coed wards, girls excreted approximately 30% more 17-OHCS per day than on all-girl wards, a significant difference probably related to psychological tension.

Submitted on December 24, 1964




This article has been cited by other articles:


Home page
 Psychosom. Med.Home page
J. W. Mason, S. Wang, R. Yehuda, H. Lubin, D. Johnson, J. D. Bremner, D. Charney, and S. Southwick
Marked Lability in Urinary Cortisol Levels in Subgroups of Combat Veterans With Posttraumatic Stress Disorder During an Intensive Exposure Treatment Program
Psychosom Med, March 1, 2002; 64(2): 238 - 246.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1965 by the American Psychosomatic Society