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Psychosomatic Medicine 28:101-113 (1966)
© 1966 American Psychosomatic Society

Stress in Subjects Undergoing Sleep Deprivation

EDWARD J. KOLLAR M.D.1, GRANT R. SLATER PH.D.1, JAMES O. PALMER PH.D.1, RICHARD F. DOCTER PH.D.1, and ARNOLD J. MANDELL M.D.1

1 Department of Psychiatry, The Neuropsychiatric Institute, UCLA Center for the Health Sciences, Los Angeles, Calif.

Psychological, physiological, and biochemical studies were conducted on 4 healthy young-adult males while they underwent 120 hr. of sleep deprivation. The subjects quickly Formed a group and dealt with this contrived stress in much the same way that groups cope with stressful environments. Although it is concluded that sleep deprivation is stressful, our measurements did not show an adrenocortical activation. The question of the psychotogenic potency of sleep deprivation is reviewed and it is concluded that sleep deprivation per se is not an adequate stimulus for the production of psychosis.

Submitted on October 18, 1965




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