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Psychosomatic Medicine 28:464-474 (1966)
© 1966 American Psychosomatic Society

Effects of Alcohol on Brain-Tissue Impedance in Animals and Man

BRUCE MACGILLIVRAY M.B., M.R.C.P.1, RAYMOND T. KADO B.S.2, and W. ROSS ADEY M.D.2

1 Department of Anatomy, and Brain Research Institute, University of California School of Medicine, Los Angeles, Los Angeles, Calif.; Wellcome Research Travel Grant recipient; present address: London, England
2 Department of Anatomy, and Brain Research Institute, University of California School of Medicine, Los Angeles, Los Angeles, Calif.

The effect of blood alcohol levels to 240 mg./lOO ml. on the impedance of the amygdala, hippocampus, lateral geniculate bodies (normal and degenerated, 1 year after striatal cortex ablation), and the midbrain reticular formation, has been examined in cats. The characteristic response to alcohol was a fall in both the reactive and resistive components of impedance. No regional differences were found. There was no significant change in impedance in the degenerated lateral geniculate bodies. The pes hippocampus of 2 human subjects showed the same response to alcohol as the normal cat brain.






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Copyright © 1966 by the American Psychosomatic Society