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Psychosomatic Medicine 28:636-650 (1966)
© 1966 American Psychosomatic Society
1 Neurology Service, Cleveland Metropolitan General Hospital, and the Division of Neurology, Western Reserve University, School, Cleveland
In this article current concepts of treatment of alcoholic intoxication and withdrawal are critically evaluated. In general, writings on this subject have two main shortcomings: (1.) a failure to define what is being treated--several different clinical disorders being treated as a single disease; and (2.) a lack of awareness of the natural history of the alcoholic diseases and the marked variability in the severity and duration of symptoms. For these reasons, the alcoholic disorders are classified and defined according to their mechanisms, insofar as these are known. Deep coma due to alcoholic intoxication represents a medical emergency, the main danger being death from respiratory depression. In regard to the withdrawal syndrome, it is important to distinguish clearly between the mild forms of this disorder (tremor and hallucinosis) and delirium tremens, which may be lethal. A wide variety of drugs are useful in controlling the milder forms but practically none are effective in preventing delirium tremens or altering the duration and mortality rate of this disorder. In the management of delirium tremens the primary aims are to replace fluids and electrolytes and to anticipate and treat shock and hyperthermia, should these supervene.
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