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Psychosomatic Medicine 30:809-818 (1968)
© 1968 American Psychosomatic Society
1 University of Vermont, Department of Medicine, Cardiovascular Research Unit, Burlington, Vt.
In view of current interest in the neurogenic and hormonal aspects of myocardial metabolic pathogenesis (mutually potentiating catecholamine- and glucocorticoid-cardiotoxicity, according to Selye), cardiac adrenergic functional and adrenocortical secretory responses were tested in normal subjects under standardized mild sensory and mental stresses. The results suggest an exaggerated stress reactivity of emotionally irritable individuals and a possible cardiopathogenic significance of common everyday annoyances in predisposed personality types.
Submitted on January 29, 1968
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