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Psychosomatic Medicine 34:424-430 (1972)
© 1972 American Psychosomatic Society

Changes in Mood During Incubation of Acute Febrile Disease and the Effects of Pre-Exposure Psychologic Status

ARTHUR CANTER PhD1

1 Department of Psychiatry, University of Iowa, Iowa City, Iowa

Address for reprint requests: Dr. A. Canter, Division of Clinical Psychology, Iowa Psychopathic Hospital, 500 Newton Road, Iowa City, Iowa 52240.

Psychologic measures of mood, distress and psychologic vulnerability were obtained from young male volunteers participating in experimental tularemia studies before exposure, during incubation of disease and during the acute and convalescent illness periods. Daily temperature and fever records were maintained. It was found that the onset of negative mood feelings was prodromal to fever in the majority of subjects. Psychologically vulnerable subjects tended to react to a greater degree and to show more severe illness as measured by the duration of fever than did the nonvulnerable subjects.

Submitted on October 6, 1971
Revised on February 7, 1971




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