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Psychosomatic Medicine 35:309-321 (1973)
© 1973 American Psychosomatic Society
1 Departments of Psychiatry and Medicine, U.C.L.A. School of Medicine, Harbor General Hospital Campus Torrance, Cal. 90509 Department of Psychiatry, Pennsylvania State University College of Medicine Hershey, Penn. 17033
Dr. Robert T. Rubin, B-4 Neurology Laboratory, Harbor General Hospital, Torrance, CA 90509
The patterns of LH, FSH and GH release during all-night sleep were studied in 16 normal young adult men, sampled on two consecutive nights. The release of both gonadotropins occurred in random, unrelated peaks that showed no consistency between subjects or from night to night in the same subject. No circadian or ultradian rhythm was discernible for either LH or FSH. When analyzed by sleep stages, LH levels showed a modest but significant increase (14%) during REM sleep compared to the other stages of sleep. FSH levels, on the other hand, showed no clear relationship to sleep stages. Growth hormone did show the usual marked increase coincident with the onset of slow wave sleep.
Submitted on July 12, 1972
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