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Psychosomatic Medicine 35:309-321 (1973)
© 1973 American Psychosomatic Society

Luteinizing Hormone, Follicle Stimulating Hormone, and Growth Hormone Secretion in Normal Adult Men During Sleep and Dreaming

ROBERT T. RUBIN MD1, PAUL R. GOUIN MD1, ANTHONY KALES MD1, and WILLIAM D. ODELL MD, PhD1

1 Departments of Psychiatry and Medicine, U.C.L.A. School of Medicine, Harbor General Hospital Campus Torrance, Cal. 90509 Department of Psychiatry, Pennsylvania State University College of Medicine Hershey, Penn. 17033

Dr. Robert T. Rubin, B-4 Neurology Laboratory, Harbor General Hospital, Torrance, CA 90509

The patterns of LH, FSH and GH release during all-night sleep were studied in 16 normal young adult men, sampled on two consecutive nights. The release of both gonadotropins occurred in random, unrelated peaks that showed no consistency between subjects or from night to night in the same subject. No circadian or ultradian rhythm was discernible for either LH or FSH. When analyzed by sleep stages, LH levels showed a modest but significant increase (14%) during REM sleep compared to the other stages of sleep. FSH levels, on the other hand, showed no clear relationship to sleep stages. Growth hormone did show the usual marked increase coincident with the onset of slow wave sleep.

Submitted on July 12, 1972
Revised on October 2, 1972







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Copyright © 1973 by the American Psychosomatic Society