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Psychosomatic Medicine, Vol 47, Issue 4 320-332, Copyright © 1985 by American Psychosomatic Society


ORIGINAL ARTICLES

Endocrine and cardiovascular responses during phobic anxiety

RM Nesse, GC Curtis, BA Thyer, DS McCann, MJ Huber-Smith and RF Knopf

In vivo exposure therapy for phobias is uniquely suited for controlled studies of endocrine and physiologic responses during psychologic stress. In this study, exposure therapy induced significant increases in subjective anxiety, pulse, blood pressure, plasma norepinephrine, epinephrine, insulin, cortisol, and growth hormone, but did not change plasma glucagon or pancreatic polypeptide. Although the subjective and behavioral manifestations of anxiety were consistent and intense, the magnitude, consistency, timing, and concordance of endocrine and cardiovascular responses showed considerable variation.


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Copyright © 1985 by the American Psychosomatic Society