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Psychosomatic Medicine, Vol 50, Issue 4 439-443, Copyright © 1988 by American Psychosomatic Society

ORIGINAL ARTICLES

Expectancy effects on respiration during lactate infusion

GM van der Molen and MA van den Hout
Department of Medical Psychology, Limburg University, Maastricht, The Netherlands.

The effect of lactate infusion on pCO2 and respiration rate was studied in two differently instructed groups of healthy volunteers in a double-blind, placebo-controlled, cross-over study. Both groups showed a significant decrease in alveolar pCO2 after lactate but not after placebo. This was accompanied by an increase in respiration rate in those subjects who had expected to become anxious and by a decrease in respiration rate in those who had expected to experience pleasant excitement.


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