Psychosomatic Medicine Tips for Better Browsing
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Bovbjerg, D. H.
Right arrow Articles by et, al.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bovbjerg, D. H.
Right arrow Articles by et, al.

Psychosomatic Medicine, Vol 54, Issue 6 623-637, Copyright © 1992 by American Psychosomatic Society

ORIGINAL ARTICLES

An experimental analysis of classically conditioned nausea during cancer chemotherapy

DH Bovbjerg, WH Redd, PB Jacobsen, SL Manne, KL Taylor, A Surbone, JP Crown, L Norton, TA Gilewski, CA Hudis and al. et
Memorial Sloan-Kettering Cancer Center, New York, New York 10021.

This study investigated classical conditioning in women undergoing outpatient adjuvant chemotherapy for breast cancer. Breast cancer chemotherapy outpatients were randomly assigned either to an Experimental Group (exposed to a distinctive stimulus before each infusion of chemotherapy) or to a Control Group. After repeated infusions of chemotherapy, patients' responses to the experimental stimulus were assessed in a location not associated with chemotherapy. Experimental Group patients had increased nausea (self-reported on a visual analog scale) following the presentation of the experimental stimulus at this test trial, whereas Control Group patients did not. Two other measures of nausea corroborated these results. Post hoc statistical analyses confirmed predictions based on conditioning theory. This conditioning model of anticipatory nausea bears witness to the relevance of classical conditioning in clinical medicine.


This article has been cited by other articles:


Home page
 Psychosom. Med.Home page
S. Klosterhalfen, A. Ruttgers, E. Krumrey, B. Otto, U. Stockhorst, R. L. Riepl, Th. Probst, and P. Enck
Pavlovian Conditioning of Taste Aversion Using a Motion Sickness Paradigm
Psychosom Med, September 1, 2000; 62(5): 671 - 677.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1992 by the American Psychosomatic Society