Psychosomatic Medicine Tips for Better Browsing
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Lapane, K. L.
Right arrow Articles by Hume, A. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lapane, K. L.
Right arrow Articles by Hume, A. L.

Psychosomatic Medicine, Vol 57, Issue 6 509-513, Copyright © 1995 by American Psychosomatic Society

ORIGINAL ARTICLES

Is a history of depressive symptoms associated with an increased risk of infertility in women?

KL Lapane, S Zierler, TM Lasater, M Stein, MM Barbour and AL Hume
Division of Health Education, Memorial Hospital, Pawtucket, Rhode Island 02860, USA.

Researchers have reported an association between self-reported antidepressant use and increased risk of ovulatory infertility but could not control for confounding by the drug indication. We evaluated the role of depressive symptoms in the development of infertility. We recontacted a population-based sample of Pawtucket Heart Health Program (PHHP) health survey respondents to perform this case-control study. Self-reported infertility was defined as an inability to conceive after 12 months of unprotected intercourse. Controls were women who reported at least one pregnancy. The index age for infertile women was the age at which they first experienced fertility problems, and for the fertile women it was the age of their first pregnancy. History of depressive symptoms was based on self-report before the index age. Women with a history of depressive symptoms were nearly twice as likely to report infertility relative to women without a history of depressive symptoms before the index age after controlling for potential confounders (90% confidence interval: 0.9-3.2). Our data suggest that depressive symptoms as well as the drugs used to treat these conditions may play an important role in the pathogenesis of infertility. The association between depressive symptoms and infertility should be explored further.


This article has been cited by other articles:


Home page
 Hum Reprod UpdateHome page
K. E. Williams, W. K. Marsh, and N. L. Rasgon
Mood disorders and fertility in women: a critical review of the literature and implications for future research
Hum. Reprod. Update, November 1, 2007; 13(6): 607 - 616.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
J.M.J. Smeenk, C.M. Verhaak, A. Eugster, A. van Minnen, G.A. Zielhuis, and D.D.M. Braat
The effect of anxiety and depression on the outcome of in-vitro fertilization
Hum. Reprod., July 1, 2001; 16(7): 1420 - 1423.
[Abstract] [Full Text] [PDF]

Home page
 JWatch PsychiatryHome page
Depression Is Associated with Infertility in Women, but How?
Journal Watch Psychiatry, February 1, 1996; 1996(201): 1 - 1.
[Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1995 by the American Psychosomatic Society