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Psychosomatic Medicine, Vol 60, Issue 1 89-91, Copyright © 1998 by American Psychosomatic Society

ORIGINAL ARTICLES

Remission of cancer chemotherapy-induced emesis during antidepressant therapy with nefazodone

HR Khouzam, AJ Monteiro and ME Gerken
VA Medical Center, Manchester, New Hampshire 03104-4098, USA.

OBJECTIVE: To emphasize the importance of treating a major depressive episode in an elderly patient with small cell lung cancer (SCLC). METHOD: A case report is described to illustrate the importance of treating depression in an elderly patient with SCLC undergoing chemotherapy. RESULTS: During the course of antidepressant therapy with nefazodone, the patient also experienced a remission of cancer chemotherapy-induced emesis. CONCLUSIONS: This case report suggests that the remission of emesis could be related to the 5-hydroxytryptamine (5-HT) antagonistic property of nefazodone.


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M. Dwight-Johnson, K. Ell, and P.-J. Lee
Can Collaborative Care Address the Needs of Low-Income Latinas With Comorbid Depression and Cancer? Results From a Randomized Pilot Study
Psychosomatics, June 1, 2005; 46(3): 224 - 232.
[Abstract] [Full Text] [PDF]


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Copyright © 1998 by the American Psychosomatic Society