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Psychosomatic Medicine, Vol 60, Issue 6 723-725, Copyright © 1998 by American Psychosomatic Society

ORIGINAL ARTICLES

Antidepressants for the virtually eviscerated patient: options instead of oral dosing

JS Koelle and JE Dimsdale
Department of Psychiatry, University of California, San Diego, La Jolla 92093-0804, USA.

OBJECTIVE: Alternate ways of administering antidepressants when oral intake is impossible are discussed. METHOD: Reviews of 1) the medical circumstances that preclude oral medication administration and 2) novel administration strategies for antidepressants were conducted. RESULTS: Consultation psychiatrists not infrequently encounter depressed patients who lack a functioning gastrointestinal tract and who thus cannot absorb oral antidepressant medication. Under these circumstances, antidepressants can be administered intravenously, by rectal suppository, or topically. CONCLUSION: There are options for administration of antidepressant medication when oral intake is impossible.




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Copyright © 1998 by the American Psychosomatic Society