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Psychosomatic Medicine 61:828-833 (1999)
© 1999 American Psychosomatic Society


ORIGINAL ARTICLE

Association Between Burnout at Work and Leukocyte Adhesiveness/Aggregation

Yehuda Lerman, MD, MPH, Samuel Melamed, PhD, Yuri Shragin, MD, Talma Kushnir, PhD, Yosef Rotgoltz, MD, Arie Shirom, PhD and Moshe Aronson, PhD

From the Occupational Health and Rehabilitation Institute, Ra’annana, and Sackler Faculty of Medicine (Y.L., S.M., Y.S., T.K., Y.R), Faculty of Management (A.S.), and Department of Cell Biology and Histology, Sackler Faculty of Medicine (M.A.), Tel-Aviv University, Tel-Aviv, Israel.

Address reprint requests to: Dr. Yehuda Lerman, Occupational Health Center, Kupat-Holim, 101 Arlozorov St., Tel-Aviv 62098, Israel.

OBJECTIVE: This study examined whether burnout at work is associated with leukocyte adhesiveness/aggregation (LAA), a phenomenon known to be affected by stress.

METHODS: The LAA levels of 179 employees (68 men and 111 women) of Tel Aviv University were determined when the employees underwent their annual routine medical checkup. Blood pressure and toxic chemical exposure were also measured, and background data were retrieved from medical records. Information on burnout and somatic complaints (known to be a general marker of stress) was collected through a self-report questionnaire.

RESULTS: Total burnout and each of its subcomponents, emotional exhaustion, chronic fatigue, and cognitive weariness, was significantly associated with LAA levels, even after controlling for age, sex, and educational level. Burnout and somatic complaints intercorrelated positively, but somatic complaints were not significantly associated with LAA levels before or after controlling for the above possible confounders.

CONCLUSIONS: Burnout was positively associated with LAA levels. This finding is consistent with the growing evidence of the negative impact of burnout on physical health. The lack of an association between somatic complaints and LAA levels reinforces the claim that burnout and stress are two different concepts.

Key Words: leukergy • burnout • somatic complaints • leukocyte adhesiveness/aggregation test • stress • exhaustion

Abbreviations: LAA = leukocyte adhesiveness/aggregation.




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