| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
REVIEW ARTICLE |
From the Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington (W.J.K.); Department of Pediatrics, University of Washington, Seattle, Washington (L.R., P.L.); Center for Health Studies, Group Health Cooperative, Seattle, Washington (P.L.); Department of Psychiatry and Behavioral Sciences, Children’s Orthopedic Hospital, Seattle, Washington (E.M.)
Address correspondence and reprint requests to Wayne J. Katon, MD, Department of Psychiatry & Behavioral Sciences, Box 356560, University of Washington School of Medicine, 1959 NE Pacific St., Seattle, WA 98195-6560. E-mail: wkaton{at}u.washington.edu
OBJECTIVE: This article reviewed the child and adult medical literature on the prevalence of comorbid anxiety disorders in patients with asthma. Theoretical ideas regarding the relatively high comorbidity rates are presented along with a model describing putative interactions between anxiety disorders and asthma.
METHOD: A search of the literature from the last 2 decades using MEDLINE by pairing the word, "asthma," with the following words: "anxiety," "depression," "panic," and "psychological disorders." We located additional research by screening the bibliographies of articles retrieved in the MEDLINE search.
RESULTS: Both adult and child/adolescent populations with asthma appear to have a high prevalence of anxiety disorders. In child/adolescent populations with asthma, up to one third may meet criteria for comorbid anxiety disorders. In adult populations with asthma, the estimated rate of panic disorder ranges from 6.5% to 24%. However, most studies are limited by small samples, nonrepresentative populations, self-reported asthma status, and lack of controlling for important potential confounders such as smoking and asthma medications. There are also limited data on the impact of anxiety comorbidity in patients with asthma on symptom burden, self-care regimens (such as monitoring peak expiratory flow, taking medication, and quitting smoking), functional status, and medical costs.
CONCLUSIONS: There appears to be a high comorbidity of anxiety disorders in patients with asthma. The prevalence and longitudinal impact of anxiety comorbidity needs to be examined in a large population-based sample of children, adolescents, and adults with asthma. If a high prevalence of comorbid anxiety disorder is documented and if this comorbidity adversely affects the self-efficacy and self-care, symptom burden, and functioning in persons with asthma, then it will be important to develop treatment trials.
Key Words: asthma, • anxiety, • medical costs.
Abbreviations: ASI = Anxiety Sensitivity Index.
This article has been cited by other articles:
 |
|
 |
|
  D. Moreau, S. Kalaboka, M. Choquet, and I. Annesi-Maesano Asthma, obesity, and eating behaviors according to the Diagnostic and Statistical Manual of Mental Disorders IV in a large population-based sample of adolescents Am. J. Clinical Nutrition, May 1, 2009; 89(5): 1292 - 1298. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. Schmitz, J. Wang, A. Malla, and A. Lesage The Impact of Psychological Distress on Functional Disability in Asthma: Results From The Canadian Community Health Survey Psychosomatics, January 1, 2009; 50(1): 42 - 49. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P.-Y. S. Chan and P. W. Davenport Respiratory-related evoked potential measures of respiratory sensory gating J Appl Physiol, October 1, 2008; 105(4): 1106 - 1113. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. P. Roy-Byrne, K. W. Davidson, R. C. Kessler, G. J.G. Asmundson, R. D. Goodwin, L. Kubzansky, R. B. Lydiard, M. J. Massie, W. Katon, S. K. Laden, et al. Anxiety Disorders and Comorbid Medical Illness Focus, September 1, 2008; 6(4): 467 - 485. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. D. Goodwin, M. E. Fischer, and J. Goldberg A Twin Study of Post Traumatic Stress Disorder Symptoms and Asthma Am. J. Respir. Crit. Care Med., November 15, 2007; 176(10): 983 - 987. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. D. Goodwin, P. Wickramaratne, Y. Nomura, and M. M. Weissman Familial Depression and Respiratory Illness in Children Arch Pediatr Adolesc Med, May 1, 2007; 161(5): 487 - 494. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. J. M. Ross, T. M. A. Davis, and D. Y. Hogg Screening and Assessing Adolescent Asthmatics for Anxiety Disorders Clin Nurs Res, February 1, 2007; 16(1): 5 - 24. [Abstract] [PDF]
|
|
|
|
|
|
L. B. Myers Commentary by Myers Clin Nurs Res, February 1, 2007; 16(1): 25 - 28. [PDF]
|
|
|
|
 |
|
 E. Lobo, P. De Jonge, F. J. Huyse, J. P.J. Slaets, M.-J. Rabanaque, and A. Lobo Early Detection of Pneumology Inpatients at Risk of Extended Hospital Stay and Need for Psychosocial Treatment Psychosom Med, January 1, 2007; 69(1): 99 - 105. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Sareen, F. Jacobi, B. J. Cox, S.-L. Belik, I. Clara, and M. B. Stein Disability and poor quality of life associated with comorbid anxiety disorders and physical conditions. Arch Intern Med, October 23, 2006; 166(19): 2109 - 2116. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. L. Lavoie, S. L. Bacon, S. Barone, A. Cartier, B. Ditto, and M. Labrecque What is worse for asthma control and quality of life: depressive disorders, anxiety disorders, or both? Chest, October 1, 2006; 130(4): 1039 - 1047. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L D Kubzansky, D Sparrow, B Jackson, S Cohen, S T Weiss, and R J Wright Angry breathing: a prospective study of hostility and lung function in the Normative Aging Study Thorax, October 1, 2006; 61(10): 863 - 868. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. J. Warner, M. A. Lumley, R. J. Casey, W. Pierantoni, R. Salazar, E. M. Zoratti, R. Enberg, and M. R. Simon Health Effects of Written Emotional Disclosure in Adolescents with Asthma: A Randomized, Controlled Trial J. Pediatr. Psychol., July 1, 2006; 31(6): 557 - 568. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W. J. Katon Clinical practice. Panic disorder. N. Engl. J. Med., June 1, 2006; 354(22): 2360 - 2367. [Full Text] [PDF]
|
|
|
|
 |
|
 J. S. Halterman, K. M. Conn, E. Forbes-Jones, M. Fagnano, A. D. Hightower, and P. G. Szilagyi Behavior Problems Among Inner-City Children With Asthma: Findings From a Community-Based Sample Pediatrics, February 1, 2006; 117(2): e192 - e199. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
