This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Petry, N. M. Articles by Wagner, J. A. Search for Related Content PubMed PubMed Citation Articles by Petry, N. M. Articles by Wagner, J. A. Related Collections Anxiety Other Psychiatric Disorders Substance Abuse Overweight or Obesity

Overweight and Obesity Are Associated With Psychiatric Disorders: Results From the National Epidemiologic Survey on Alcohol and Related Conditions

From the Departments of Psychiatry (N.M.P., D.B., R.H.P.), and Behavioral Sciences and Community Health (J.A.W.), University of Connecticut Health Center, Farmington, Connecticut.

Address correspondence and reprint requests to Nancy M. Petry, PhD, Department of Psychiatry, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030-3944. E-mail: petry{at}psychiatry.uchc.edu

Objective: This study evaluated associations between body mass index (BMI) and psychiatric disorders.

Methods: Data from 41,654 respondents in the National Epidemiologic Survey on Alcohol and Related Conditions were analyzed.

Results: After controlling for demographics, the continuous variable of BMI was significantly associated with most mood, anxiety, and personality disorders. When persons were classified into BMI categories of underweight, normal weight, overweight, obese, and extremely obese, both obese categories had significantly increased odds of any mood, anxiety, and alcohol use disorder, as well as any personality disorder, with odds ratios (ORs) ranging from 1.21 to 2.08. Specific Diagnostic and Statistical Manual of Mental Disorders-revision IV mood and personality disorders associated with obesity included major depression, dysthmia, and manic episode (ORs, 1.45–2.70) and antisocial, avoidant, schizoid, paranoid, and obsessive-compulsive personality disorders (ORs, 1.31–2.55). Compared with normal weight individuals, being moderately overweight was significantly associated with anxiety and some substance use disorders, but not mood or personality disorders. Specific anxiety disorders that occurred at significantly higher rates among all categories of persons exceeding normal weight were generalized anxiety, panic without agoraphobia, and specific phobia (ORs, 1.23–2.60). Being underweight was significantly related to only a few disorders; it was positively related to specific phobia (OR, 1.31) and manic episode (OR, 1.83), and negatively associated with social phobia (OR, 0.60), panic disorder with agoraphobia (OR, 0.40), and avoidant personality disorder (OR, 0.59).

Conclusion: These data provide a systematic and comprehensive assessment of the association between body weight and psychiatric conditions. Interventions addressing weight loss may benefit from integrating treatment for psychiatric disorders.

Key Words: obesity • overweight • BMI • mood disorders • anxiety disorders • substance use disorders • personality disorders

Abbreviations: NIAAA = National Institute on Alcohol Abuse and Alcoholism; NESARC = National Epidemiologic Survey on Alcohol and Related Conditions; AUDADIS = Alcohol Use Disorder and Associated Disabilities Interview Schedule; DSM-IV = Diagnostic and Statistical Manual of Mental Disorders- Fourth Edition; BMI = body mass index; OR = odds ratio; CI = confidence intervals.

This article has been cited by other articles:

				Y. K. Wing, S. X. Li, A. M. Li, J. Zhang, and A. P. S. Kong The Effect of Weekend and Holiday Sleep Compensation on Childhood Overweight and Obesity Pediatrics, November 1, 2009; 124(5): e994 - e1000. [Abstract] [Full Text] [PDF]

				M. Kivimaki, G. D. Batty, A. Singh-Manoux, H. Nabi, S. Sabia, A. G. Tabak, T. N. Akbaraly, J. Vahtera, M. G. Marmot, and M. Jokela Association between common mental disorder and obesity over the adult life course The British Journal of Psychiatry, August 1, 2009; 195(2): 149 - 155. [Abstract] [Full Text] [PDF]

				A. Terracciano, A. R. Sutin, R. R. McCrae, B. Deiana, L. Ferrucci, D. Schlessinger, M. Uda, and P. T. Costa Jr Facets of Personality Linked to Underweight and Overweight Psychosom Med, July 1, 2009; 71(6): 682 - 689. [Abstract] [Full Text] [PDF]

				S. Benson, S. Hahn, S. Tan, K. Mann, O.E. Janssen, M. Schedlowski, and S. Elsenbruch Prevalence and implications of anxiety in polycystic ovary syndrome: results of an internet-based survey in Germany Hum. Reprod., June 1, 2009; 24(6): 1446 - 1451. [Abstract] [Full Text] [PDF]

				T. Paparrigopoulos, E. Tzavellas, D. Karaiskos, and I. Liappas Thyroid Function and Body Weight in Psychiatric Disorders Arch Intern Med, December 8, 2008; 168(22): 2497 - 2497. [Full Text] [PDF]

				H. Baumeister and M. Harter Overweight And Obesity Are Associated With Psychiatric Disorders: Are They? Psychosom Med, November 1, 2008; 70(9): 1060 - 1060. [Full Text] [PDF]

				D. Barry, N. M. Petry, R. H. Pietrzak, and J. Wagner Response Psychosom Med, November 1, 2008; 70(9): 1060 - 1061. [Full Text] [PDF]

				A. I. F. Blakemore and P. Froguel Is Obesity Our Genetic Legacy? J. Clin. Endocrinol. Metab., November 1, 2008; 93(11_Supplement_1): s51 - s56. [Abstract] [Full Text] [PDF]

				G. K. Andrikopoulos and S. Tzeis Modification of Cardiometabolic Risk Through Cannabinoid Type-1 Receptor Antagonism Angiology, August 1, 2008; 59(2_suppl): 44S - 48S. [Abstract] [PDF]