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Anxiety Reduces Baroreflex Cardiac Control in Older Adults With Major Depression

Lana L. Watkins, PhD, Paul Grossman, PhD, Ranga Krishnan, MD and James A. Blumenthal, PhD

From the Duke University Medical Center, Department of Psychiatry and Behavioral Sciences, Durham, North Carolina (L.L.W., R.K., J.A.B.); and Hebrew Rehabilitative Center for the Aged, Boston, Massachusetts (P.G.).



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  		Fig. 1. Correlation between baroreflex control of HR and state anxiety scores in subjects with MDD (N = 56; BRCSPEC = 10.8 - 0.1 x ST-ANX).

 


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  		Fig. 2. Baroreflex control of HR in volunteers separated by quartile of ST-ANX score. Baroreflex control was estimated as the magnitude of the transfer function relating R-R interval oscillations to SBP oscillations across the low-frequency band (0.07–0.129 Hz). Points shown represent mean ± SEM.

 




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