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Caregiving May Be Hazardous to Your Health

Department of Psychiatry, University of California, San Diego, and VA San Diego Healthcare System, La Jolla, CA 92093-0680, Email: igrant@ucsd.edu

View larger version (13K): [in a new window]   Fig. 1. General model linking perceived stress to physiological response. ACTH = adrenocorticotropic hormone; BP = blood pressure; CAMS = cellular adhesion molecules; CNS = central nervous system; CRH = corticotropin-releasing hormone; CVR = change in cardiovascular reactivity; E = epinephrine; NE = norepinephrine; NK = natural killer lymphocyte; NPY = neuropeptide Y; NS = nonsympathetic; ß2 = ß2-adrenergic receptor.

View larger version (32K): [in a new window]   Fig. 2. Hypothetical physiologic responses of chronically stressed caregivers who are "adapted" to caregiving situation (eg, adequate social supports and coping skills are available) vs. those who are "maladapted." ACTH = adrenocorticotropic hormone; BP = blood pressure; CAMS = cellular adhesion molecules; CRH = corticotropin releasing hormone; CVR = change in cardiovascular reactivity; E = epinephrine; HR = heart rate; NE = norepinephrine; NK = natural killer lymphocyte; NPY = neuropeptide Y; ß2 = ß2-adrenergic receptor.