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The Very Model of a Modern Etiology: A Biopsychosocial View of Peptic Ulcer

Susan Levenstein, MD

From the Gastroenterology Department, San Camillo-Forlanini Hospital, Rome, Italy.



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  		Fig. 1. References found by a MEDLINE search with the keywords "peptic ulcer" and "psychological stress," in proportion to all MEDLINE references for each period and in proportion to all MEDLINE references with the keyword "peptic ulcer."

 


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  		Fig. 2. Components of the observed association between stress and peptic ulcer.

 


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  		Fig. 3. A model postulating behavioral and psychophysiologic mechanisms that may link psychosocial stress with peptic ulcer. NSAIDs = nonsteroidal antiinflammatory drugs.

 




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