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Acute Psychological Stress and Exercise and Changes in Peripheral Leukocyte Adhesion Molecule Expression and Density

From the Department of Psychiatry (M.U.G, P.J.M.), University of California, San Diego, La Jolla, CA; and the Department of Medical Psychology (M.U.G.), University of Essen, Essen, Germany.

View larger version (21K): [in a new window]   Fig. 1. L-selectin (CD62L) density (number of PE molecules bound per cell) in response to a speaking and an exercise task. In response to public speaking (top), the surface density of CD62L was decreased, but not significantly, on mixed lymphocytes, CD8+ cytotoxic cells, and CD4+ helper T cells. In response to exercise (bottom), the surface density of CD62L was significantly decreased on mixed lymphocytes, CD8+ cytotoxic cells, and CD4+ helper T cells (p values < .001).

View larger version (17K): [in a new window]   Fig. 2. LFA-1 (CD11a) density (number of PE molecules bound per cell) on lymphocytes in response to speaking and exercise tasks. The surface density of CD11a on lymphocytes was greater after both the exercise (p < .001) and speaking (p < .01) tasks.