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Efficacy and Safety of Fluoxetine in the Treatment of Patients With Major Depression After First Myocardial Infarction: Findings From a Double-Blind, Placebo-Controlled Trial

Jacqueline J. M. H. Strik, MD, Adriaan Honig, MD, PhD, MRCPsych, Richel Lousberg, PhD, Aimée H. P. Lousberg, Emile C. Cheriex, MD, PhD, Hanneke G. Tuynman-Qua, MD, MFPM, Petra M. J. C. Kuijpers, MD, H. J. J. Wellens, MD, PhD and H. M. Van Praag, MD, PhD

From the Departments of Psychiatry (J.J.M.H.S., A.H., A.H.P.L., P.M.J.C.K., H.M.V.P.) and Cardiology (E.C.C., P.M.J.C.K., M.F.P.M.H.J.J.W.), University Hospital Maastricht; Department of Psychiatry (J.J.M.H.S., A.H., R.L.), University of Maastricht; and Eli Lilly Netherlands (H.G.T.-Q.), Nieuwegein, The Netherlands.



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  		Fig. 1. Flow chart of depressed patients eligible for the study.

 


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  		Fig. 2. Efficacy of fluoxetine vs. placebo in depression in post-MI depression. w = week.

 


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  		Fig. 3. Efficacy of fluoxetine vs. placebo in hostility in post-MI depression. w = week. {star}p = .05.

 




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