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Decreased Human Circadian Pacemaker Influence After 100 Days in Space: A Case Study

From the Clinical Neuroscience Research Center (T.H.M., K.S.K., L.R.R.), Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, PA; and Linenger Communications (J.M.L.), Suttons Bay, MI.

View larger version (17K): [in a new window]   Fig. 1. Power frequency spectra for oral temperature and subjective alertness circadian rhythms. Plotted separately for block 1 (days 37–50), block 2 (days 79–91), and block 3 (days 110–122) is the square of the amplitude of the best-fitting sinusoid at each period length.

View larger version (20K): [in a new window]   Fig. 2. Time-of-day functions for oral temperature and subjective alertness. Plotted separately for block 1 (days 37–50), block 2 (days 79–91), and block 3 (days 110–122) is the mean value per 3-hour time-of-day bin. Each mean is derived from 6 to 14 data points.