Psychosomatic Medicine
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Abstract Freely available
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Mason, J. W.
Right arrow Articles by Southwick, S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mason, J. W.
Right arrow Articles by Southwick, S.
Related Collections
Right arrow Neuroendocrine
Right arrow PTSD

Marked Lability in Urinary Cortisol Levels in Subgroups of Combat Veterans With Posttraumatic Stress Disorder During an Intensive Exposure Treatment Program

John W. Mason, MD, Sheila Wang, PhD, Rachel Yehuda, PhD, Hadar Lubin, MD, David Johnson, PhD, J. Douglas Bremner, MD, Dennis Charney, MD and Steven Southwick, MD

From the Department of Psychiatry, Yale University School of Medicine, New Haven, and National Center for PTSD, Clinical Neuroscience Division, Veterans Affairs Medical Center, West Haven, CT (J.M., S.W., H.L., D.J., J.D.B., D.C., S.S.); and the Department of Psychiatry, Mount Sinai Medical School, New York, and Bronx Veterans Affairs Hospital, Bronx, NY.



View larger version (42K):

[in a new window]
  		Fig. 1. Marked lability in urinary cortisol levels in individual PTSD inpatients participating in an intensive 3-month treatment and research program in the National Center for PTSD (N = 51).

 


View larger version (17K):

[in a new window]
  		Fig. 2. Direction and magnitude of urinary cortisol level change in individual PTSD inpatients between the period of hospital admission and the midcourse period representing the peak of group and exposure treatment. The delta value was calculated as the midcourse value minus the admission value. Three subgroups (sg-A, sg-B, sg-C) are defined on the basis of dividing the distribution curve into terciles: sg-A = bottom tercile subgroup with greatest decreases; sg-B = middle tercile subgroup with the least amount of changes; sg-C = top tercile with greatest increases.

 


View larger version (20K):

[in a new window]
  		Fig. 3. Marked differences in longitudinal urinary cortisol lability patterns in PTSD patient subgroups participating in an intensive 3-month treatment and research program in the National Center for PTSD. PTSD inpatient subgroups are based on cortisol change from admission to midcourse: sg-A = bottom tercile subgroup with greatest decreases; sg-B = middle tercile subgroup with the least amount of changes; sg-C = top tercile with greatest increases; pilot = pilot study sample involving a much less intensive clinical setting.

 




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2002 by the American Psychosomatic Society