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Depression and Coronary Artery Atherosclerosis and Reactivity in Female Cynomolgus Monkeys

Carol A. Shively, PhD, J. Koudy Williams, DVM, Kathy Laber-Laird, DVM and Raymond F. Anton, PhD

From Wake Forest University School of Medicine (C.A.S., J.K.W.), Winston–Salem, NC; and Medical University of South Carolina (K.L.-L., R.F.A.), Charleston, SC.



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  		Fig. 1. Experimental design.

 


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  		Fig. 2. Nighttime baseline heart rate (2400–0400) recorded during the single-caging phase (N = 25) and 2, 13, and 24 months after the second (and final) social groups were formed.

 


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  		Fig. 3. Dexamethasone suppression test: percent decrease in cortisol concentration recorded during the single-caging phase and 5, 20, and 27 months after the second (and final) social groups were formed.

 




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