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Healthy Older Adults’ Sleep Predicts All-Cause Mortality at 4 to 19 Years of Follow-Up

Mary Amanda Dew, PhD, Carolyn C. Hoch, PhD, Daniel J. Buysse, MD, Timothy H. Monk, PhD, Amy E. Begley, MA, Patricia R. Houck, MSH, Martica Hall, PhD, David J. Kupfer, MD and Charles F. Reynolds, III, MD

From the Departments of Psychiatry (M.A.D., C.C.H., D.J.B., T.H.M., A.E.B., P.R.H., M.H., D.J.K., C.F.R.), Epidemiology (M.A.D.), and Psychology (M.A.D.), University of Pittsburgh School of Medicine and Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania.



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Fig. 1. Kaplan-Meier survival curves. a, Survival as a function of sleep latency (log-rank test = 9.63, p = .002). b, Survival as a function of sleep efficiency (log-rank test = 11.60, p = .0007). c, Survival as a function of percentage of REM sleep (log-rank test = 6.58, p = .010). df = 1 for all tests. Mean survival times (in weeks) were 614 and 752 for greater and lesser sleep latency, respectively; 624 and 754 for lesser and greater sleep efficiency, respectively; and 608 and 751 for extreme percentage of REM sleep and less extreme percentage of REM sleep. + = censored observation.

 





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