Depression and Coronary Heart Disease in Women With Diabetes
Ray E. Clouse, MD,
Patrick J. Lustman, PhD,
Kenneth E. Freedland, PhD,
Linda S. Griffith, MSW,
Janet B. McGill, MD and
Robert M. Carney, PhD
From the Departments of Psychiatry (R.E.C., P.J.L., K.E.F., L.S.G., R.M.C.) and Medicine (R.E.C., J.B.McG), Washington University School of Medicine, and the Department of Veterans Affairs (P.J.L.), Medical Center, St. Louis, Missouri.
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Fig. 1. Kaplan-Meir plots showing the development of clinically manifest coronary heart disease (CHD) in relation to depression status. Depressed subjects met criteria for major depression at the time of the index interview. The curves were significantly different across the 10 years (p < .01).
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Fig. 2. Occurrence of coronary heart disease using Kaplan-Meir analysis with further division by depression history. Currently depressed subjects met criteria at the time of the index evaluation, whereas those with remote histories reported symptoms of major depression in the past. The remainder never met psychiatric diagnostic criteria for major depressive episode. The curves for the latter two groups were not significantly different (p > .5).
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Fig. 3. Kaplan-Meir plots showing the occurrence of clinically manifest A, peripheral vascular disease (PVD) and B, cerebrovascular disease (CVD) in relation to depression status. Depressed subjects met criteria for major depression at the time of the index interview. Depressed subjects did not differ from nondepressed subject in either comparison (p > .3 for each).
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Copyright © 2003 by the American Psychosomatic Society
