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High Plasma Levels of N-Terminal Pro-Atrial Natriuretic Peptide Associated With Low Anxiety in Severe Heart Failure

Christoph Herrmann-Lingen, MD, Lutz Binder, MD, Michael Klinge, MS, Julia Sander, MS, Wiebke Schenker, MS, Beate Beyermann, MD, Dirk von Lewinski, MD and Burkert Pieske, MD

From the Departments of Psychosomatics and Psychotherapy (C.HL., M.K.), Cardiology (B.B., D.VL., B.P.), and Clinical Chemistry (L.B., J.S., W.S.), University of Göttingen, Göttingen, Germany.



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  		Fig. 1. Z-standardized psychological and quality-of-life scores by severity of congestive heart failure. NYHA = New York Heart Association functional class; NYHA 0 = no known heart disease; QoL = Quality of Life.

 


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  		Fig. 2. Observed and predicted z-standardized anxiety scores by severity of congestive heart failure. NYHA = New York Heart Association functional class; NYHA 0 = no known heart disease. Prediction based on vital exhaustion, depression, and age.

 


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  		Fig. 3. Observed and predicted z-standardized anxiety scores by severity of congestive heart failure. NYHA = New York Heart Association functional class; NYHA 0 = no known heart disease. Prediction based on vital exhaustion, depression, and age plus pro-ANP plasma levels.

 




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