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Change in Forced Expiratory Volume in 1 Second After Sham Bronchoconstrictor in Suggestible but Not Suggestion-Resistant Asthmatic Subjects

A Pilot Study

Richard Leigh, MBChB, Glenda MacQueen, MD, PhD, Gervais Tougas, MD, Frederick E. Hargreave, MD and John Bienenstock, MD

From the Firestone Institute for Respiratory Health (R.L., F.E.H.) and the Brain Body Institute (G.M., G.T., J.B.), St. Joseph’s Healthcare, McMaster University, Hamilton, Ontario, Canada.



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  		Fig. 1. Changes in FEV1 from baseline values in suggestible and nonsuggestible subjects after the inhalation of saline as a sham bronchoconstrictor (A) and sham bronchodilator (B). C, Change in FEV1 after the inhalation of saline as part of the methacholine test in suggestible (open circles) and nonsuggestible (open triangles) subjects.

 




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