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Biological Correlates of Abuse in Women with Premenstrual Dysphoric Disorder and Healthy Controls

Susan S. Girdler, PhD, Andrew Sherwood, PhD, Alan L. Hinderliter, MD, Jane Leserman, PhD, Nancy L. Costello, PhD, Patricia A. Straneva, PhD, Cort A. Pedersen, MD and Kathleen C. Light, PhD

From the Departments of Psychiatry (S.S.G., J.L., P.A.S., C.A.P., K.C.L.), Cardiology (A.L.H.), and Dentistry (N.L.C.), University of North Carolina at Chapel Hill and Psychiatry (A.S.), Duke University Medical Center, Durham, North Carolina.



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Fig. 1. Change in plasma norepinephrine during stressors in controls (top panel) and PMDD women (bottom panel) as a function of abuse histories and menstrual cycle phase.

 


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Fig. 2. Change in plasma cortisol during stress in controls (top panel) and PMDD women (bottom panel) as a function of abuse histories and menstrual cycle phase.

 


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Fig. 3. Change in cardiac output during stressors in controls (top panel) and PMDD women (bottom panel) as a function of abuse histories and menstrual cycle phase.

 





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