Baroreceptor Reflex and Integrative Stress Responses in Chronic Fatigue Syndrome
Arnold Peckerman, PhD,
John J. LaManca, PhD,
Bushra Qureishi, MD,
Kristina A. Dahl, MD,
Roseli Golfetti, PhD,
Yoshiharu Yamamoto, PhD and
Benjamin H. Natelson, MD
From the VA Medical Center, East Orange, New Jersey (A.P, B.H.N.); the CFS Cooperative Research Center, Department of Neurosciences, University of Medicine and Dentistry of New Jersey, Newark, New Jersey (A.P., B.Q., K.A.D., B.H.N.); the Heart Failure Center, Division of Circulatory Physiology, New York Presbyterian Hospital, New York, New York (J.J.L.); the Exercise Physiology Laboratory, State University of Campinas, Sãn Paulo, Brazil (R.G.); and the Educational Physiology Laboratory, Graduate School of Education, University of Tokyo, Tokyo, Japan (Y.Y.).
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Fig. 1. BRS, SBP, DBP, and HR responses to the cold pressor and speech stressors in the severe CFS (N = 15), less severe CFS (N = 16), and control (N = 29) groups. Both stressors elicited significant increases in SBP and DBP (p values <.0001). HR increased and BRS declined during the speech task (p values <.0001) but remained unchanged during the cold pressor test.
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Fig. 2. Relationships between changes in BRS, SBP, and HR during the speech task for the combined sample of patients with CFS and controls.
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Fig. 3. AD ACL energy scores, the mean symptom severity ratings, and blood pressure responses during the speech task. In the patients with less severe CFS, low SBP and DBP responses were predicted, respectively, by lower energy scores (R = .57, p < .03) and greater mean symptom severity ratings (R = -.76, p < .001). None of these relationships were significant in the severe CFS group (p > .13).
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Copyright © 2003 by the American Psychosomatic Society
