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Impact of Pain on Depression Treatment Response in Primary Care

From the Regenstrief Institute and the Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana (M.J.B., G.J.E., T.W.C., K.K.); Eli Lilly and Co., Indianapolis, Indiana (R.L.R.); Rand Health, Arlington, Virginia (T.W.C.); and Galt Associates Adjunct and the University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (P.E.S.).

View larger version (31K): [in a new window]   Fig. 1. Increased risk of poor depression treatment response at 3 months according to baseline pain severity. Odds ratios were estimated by logistic regression models using patients without pain as the reference group and are statistically significant for moderate and severe pain.

View larger version (22K): [in a new window]   Fig. 2. Increased risk of poor health-related quality of life outcomes at 3 months, defined as the lowest quartile for each SF-36 scale. Odds ratios were estimated by logistic regression models as described in Figure 1.