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Impact of Depressive Mood on Relapse in Patients With Inflammatory Bowel Disease: A Prospective 18-Month Follow-Up Study

Christian Mittermaier, MD*, Clemens Dejaco, MD*, Thomas Waldhoer, PhD, Anna Oefferlbauer-Ernst, MD, Wolfgang Miehsler, MD, Markus Beier, MD, Wolfgang Tillinger, MD, Alfred Gangl, MD and Gabriele Moser, MD

From the Department of Medicine IV, Division of Gastroenterology and Hepatology (C.D., A.O. W.M., M.B., W.T., A.G., G.M.), Department of Physical Medicine and Rehabilitation (C.M.), and Department of Epidemiology, Institute of Tumor Biology (T.W.), University Hospital of Vienna, Vienna, Austria.



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Fig. 1. BDI scores remained stable during the 18 months of follow-up. Patients with IBD were divided into depressed (BDI >=13) and nondepressed subjects (BDI <13) at baseline.

 


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Fig. 2. Patients with depression (BDI >=13) were at risk for an earlier relapse than nondepressed subjects (BDI <13); *p <.05. Arrows indicate median time to first relapse.

 





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