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Interactions Between Autonomic Nervous System Activity and Endothelial Function: A Model for the Development of Cardiovascular Disease

Kelly F. Harris, MS and Karen A. Matthews, PhD

From the Department of Psychology, University of Pittsburgh (K.F.H.), and the Departments of Psychiatry, Epidemiology, and Psychology, University of Pittsburgh School of Medicine, (K.A.M.), Pittsburgh, PA.



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Figure 1. Model of associations between psychosocial factors, autonomic nervous system regulation, and endothelial function.

 


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Figure 2. Normal interactions between the autonomic nervous system and endothelium in regulating smooth muscle tone.

 


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Figure 3. Indirect associations between autonomic nervous system regulation and endothelial function.

 





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