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Patients With Carcinoid Syndrome Exhibit Symptoms of Aggressive Impulse Dysregulation

Sascha Russo, MD, Jim C. Boon, MD, Ido P. Kema, PhD, Pax H.B. Willemse, MD, PhD, Johan A. den Boer, MD, PhD, Jakob Korf, PhD and Elisabeth G.E. de Vries, MD, PhD

From the Departments of Biological Psychiatry (S.R., J.C.B., J.S.d.B., J.K.), Laboratory Medicine (I.P.K.), and Medical Oncology (P.H.B.W., E.G.E.d.V), University Hospital Groningen, the Netherlands.



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Figure 1. Plasma levels of tryptophan correlate negatively with 24-hour urinary excretion of 5-HIAA in carcinoid patients (p = .001; r = –0.66). Open dots refer to patients not suffering from impulse control dysregulation.

 





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