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Exaggerated Platelet and Hemodynamic Reactivity to Mental Stress in Men With Coronary Artery Disease

From the Psychobiology Group, Department of Epidemiology and Public Health (P.C.S., K.M., L.B., S.E., A.S.) and the Department of Medicine (J.R.M.), University College London, London, UK.

View larger version (18K): [in a new window]   Figure 1. Mean systolic blood pressure (upper panel) and diastolic blood pressure (lower panel) for 5 periods: baseline, average of task trials, and 25 to 30 minutes, 70 to 75 minutes, and 115 to 120 minutes after stress. Solid lines = coronary artery disease patients; dashed lines = healthy controls.

View larger version (17K): [in a new window]   Figure 2. Mean heart rate (upper panel) and subjective stress (lower panel) over the 5 trials. For details, see legend to Figure 1. Solid lines = coronary artery disease patients; dashed lines = healthy controls.

View larger version (17K): [in a new window]   Figure 3. Mean total peripheral resistance (upper panel) and cardiac index (lower panel) over the 5 trials. For details, see legend to Figure 1. Solid lines = coronary artery disease patients; dashed lines = healthy controls.

View larger version (12K): [in a new window]   Figure 4. Mean percentage of platelet-leukocyte aggregates at baseline, stress, 30 minutes after stress, and 75 minutes after stress. Solid lines = coronary artery disease patients; dashed lines = healthy controls. Error bars are standard error of the mean.