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Erectile Dysfunction: Evaluation and New Treatment Options

Culley C. Carson, MD

From the Division of Urology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.



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  		Figure 1. Mechanism of penile erection and the nitric oxide/cyclic guanosine monophosphate-enhancing effect of phosphodiesterase type 5 isoenzyme inhibitors. NANC = nonadrenergic-noncholinergic neurons; NO = nitric oxide; cGMP = cyclic guanosine monophosphate; PDE5 = phosphodiesterase type 5. (Adapted from Sadovsky R, Miller T, Moskowitz M, Hackett G. Three-year update of sildenafil citrate [Viagra®] efficacy and safety. Int J Clin Pract 2001;55:115–128.)

 




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