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Altered Cortisol Response to Psychologic Stress in Breast Cancer Survivors With Persistent Fatigue

Julienne E. Bower, PhD, Patricia A. Ganz, MD and Najib Aziz, MD

From the Cousins Center for Psychoneuroimmunology (J.E.B.), UCLA Neuropsychiatric Institute, the Department of Psychiatry and Biobehavioral Sciences (J.E.B.), David Geffen School of Medicine at UCLA, the Division of Cancer Prevention and Control Research (J.E.B., P.A.G.), Jonsson Comprehensive Cancer Center at UCLA, UCLA Schools of Medicine and Public Health (P.A.G.), and UCLA Department of Pathology and Laboratory Medicine (N.A.), Los Angeles, CA.



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Figure 1. Mean salivary free cortisol levels before, during, and after experimental psychologic stress in fatigued and nonfatigued breast cancer survivors. The stressor occurred during the first 30 minutes indicated on the graph. Error bars represent 1 standard error. *p <.05.

 





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