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Salivary Cortisol as a Predictor of Postoperative Fatigue

G. James Rubin, PhD, Matthew Hotopf, PhD, Andrew Papadopoulos, PhD and Anthony Cleare, PhD

From the Section of General Hospital Psychiatry, Division of Psychological Medicine, Institute of Psychiatry and Guy’s, King’s and St. Thomas’ School of Medicine, King’s College London, London, UK (G.J.R., M.H., A.C.); the Section of Neurobiology of Mood Disorders, Division of Psychological Medicine, Institute of Psychiatry, King’s College London, London, UK (G.J.R., A.C.); and the Affective Disorders Unit, Bethlem Royal Hospital, South London and Maudsely NHS Trust, London, UK (A.P., A.C.).



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  		Figure 1. Bimodal fatigue scores 6 months after surgery. A score of 4 or more indicates clinically significant fatigue. Participants with clinically significant fatigue and who also reported having been fatigued for 6 months or more were classified as chronic fatigue cases.

 




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