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Reported Sexual Abuse Predicts Impaired Functioning but a Good Response to Psychological Treatments in Patients With Severe Irritable Bowel Syndrome

Francis Creed, MD, FRCP, Elspeth Guthrie, MD, Joy Ratcliffe, MRCPsych, Lakshmi Fernandes, MRCPsych, Christine Rigby, MSc, Barbara Tomenson, MSc, Nicholas Read, MD and David G. Thompson, FRCP

From the School of Psychiatry and Behavioural Science (F.C., E.G., J.R., B.T.) and Section of Gastrointestinal Science (D.G.T.), University of Manchester, Manchester, UK; and University of Sheffield Centre for Human Nutrition, Northern General Hospital, Manchester, UK (L.F., N.R.); all on behalf of the North of England IBS Research Group (Chris Babbs, Joe Barlow, Chandu Bardhan, Francis Creed, David Dawson, Lakshmi Fernandez, Elspeth Guthrie, Stephanie Howlett, Linda McGowan, Jane Martin, Jim Moorey, Kierran Moriarty, Stephen Palmer, Joy Ratcliffe, Nicholas Read, Christine Rigby, Irene Sadowski, David Thompson, Barbara Tomenson).



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Figure 1. The relationship between reported abuse and outcome (SF-36 physical function score) with SCL-90 somatization score as possible mediators (p values adjusted for age, sex, and marital status)

 


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Figure 2. SF36 scores by abuse categories at baseline and follow-up (treated patients only)

 


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Figure 3. Scores for treated patients only (psychotherapy and antidepressant groups) for SF-36 physical (A) and mental (B) component summary scores and SCL-90 somatization scores (C) at baseline, after 3 months of treatment, and at follow-up 1 year after end of treatment.

 


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Figure 3. (Continued)

 





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