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Hostility Scores Are Associated With Increased Risk of Cardiovascular Events in Women Undergoing Coronary Angiography: A Report from the NHLBI-Sponsored WISE Study

Marian B. Olson, MS, David S. Krantz, PhD, Sheryl F. Kelsey, PhD, Carl J. Pepine, MD, George Sopko, MD, Eileen Handberg, PhD, William J. Rogers, MD, Gretchen L. Gierach, MPH, Candace K. McClure, BS, C. Noel Bairey Merz, MD for the WISE Study Group

From the Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA (M.B.O., S.F.K., G.L.G., C.K.M.); The Uniformed Services University of Health Sciences, Bethesda, Maryland (D.S.K.); Division of Cardiology, Department of Medicine, University of Florida, Gainesville, FL (C.J.P., E.H.); National Institute of Medicine, NHLBI, Bethesda, Maryland (G.S.); Division of Cardiology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL (W.J.R.); and Department of Medicine, Cedars-Sinai Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA (C.N.B.M.)



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Figure 1. Survival curve of adverse events (defined as hospitalization for angina, nonfatal MI, CHF, stroke, other vascular events and death) by the median split of the total CMHS (sum of the cynicism, aggressive responding, and hostile affect portions of the Cook Medley Hostility).

 





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