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A Greater Reduction in High-Frequency Heart Rate Variability to a Psychological Stressor is Associated With Subclinical Coronary and Aortic Calcification in Postmenopausal Women

From the Departments of Psychiatry (P.J.G., F.Z., J.F.O., K.A.M.), Epidemiology (L.H.K., K.A.M.), and Psychology (K.A.M.), the Cardiovascular Institute (D.E.), University of Pittsburgh, Pittsburgh, Pennsylvania; and the Department of Psychology, University of South Florida, Tampa, Florida (K.S.).

View larger version (21K): [in a new window]   Figure 1. Unadjusted mean change (± standard error of mean) in high-frequency heart rate variability (HF-HRV) from a resting baseline to a speech preparation task in 79 postmenopausal women with Agatston calcium scores falling in the lower, middle, and upper tertiles of the coronary (bottom) and aortic (top) calcium score distributions. The range of calcium scores for each tertile is shown in parentheses along the abscissa. Changes in HF-HRV to the speech preparation task were assessed a median of 282 days (range, 0–754 days) before coronary and aortic calcium scores were obtained.