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Genes Making One Feel Blue in the Flow of Daily Life: A Momentary Assessment Study of Gene-Stress Interaction

Nele Jacobs, PhD, Fruhling Rijsdijk, PhD, Catherine Derom, PhD, Robert Vlietinck, MD, PhD, Phillipe Delespaul, PhD, Jim van Os, MD, PhD and Inez Myin-Germeys, PhD

From the Department of Psychiatry and Neuropsychology (N.J., P.D., J.v.O., I.M.-G.), South-Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, Maastricht, The Netherlands; the Social, Genetic & Developmental Psychiatry Research Centre (F.R.), Institute of Psychiatry, London, United Kingdom; the Faculty of Medicine (C.D.), Center for Human Genetics, Catholic University Leuven, Leuven, Belgium; the Department of Population Genetics (R.V.), Maastricht University, Maastricht; The Netherlands; the Division of Psychological Medicine (J.v.O.), Institute of Psychiatry, London, United Kingdom; and Mondriaan Zorggroep, Section Social Cognition (I.M.-G.), Heerlen, The Netherlands.


Figure 14
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Figure 1. Path diagram with the estimates of the AE model. The phenotypic variance of stress reactivity in each twin is determined by additive genetic factors (A) and individual-specific enviromental factors (E). Path estimates (A, E), are the standardized regression coefficients. The square of these estimates represent the proportion of variance they account for.

 





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