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Ethnicity, Perceived Discrimination, and Vascular Reactivity to Phenylephrine

From the San Diego State University & University of California, San Diego Joint Doctoral Program in Clinical Psychology, San Diego, California (K.S.T.); the Departments of Psychiatry (R.A.N., J.E.D.) and Medicine (M.G.Z.), University of California, San Diego, California; and the Department of Psychology, San Diego State University, San Diego, California (V.L.M.).

View larger version (15K): [in a new window]   Figure 1. Effects of ethnicity and perceived discrimination on diastolic pressor response. For visual purposes, perceived discrimination was dichotomized into high and low groups using median split. Individuals who perceive more ethnic discrimination have greater blood pressure responses to phenylephrine (p < .05).

View larger version (9K): [in a new window]   Figure 2. Path model relating ethnicity and perceived discrimination to diastolic pressor responses to phenylephrine (PE). (A) The direct relationship between ethnicity and diastolic pressor responses to PE. (B) The indirect relationship between ethnicity and diastolic pressor responses to PE through perceived discrimination. After controlling for covariates (age, body surface area, cigarette smoking, baseline blood pressure), perceived discrimination mediated the relationship between ethnicity and diastolic pressor responses to PE.