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Anticipatory Cognitive Stress Appraisal and the Acute Procoagulant Stress Response in Men

From the Department of Clinical Psychology and Psychotherapy, University of Zurich, Zurich, Switzerland (P.H.W., U.E., L.E., K.R., S.G., J.G.); the Department of Medical Psychology, University Hospital of Essen Medical School, Essen, Germany (S.E.); the Department of General Internal Medicine, University Hospital Berne, Berne, Switzerland (R.v.K.); and the Psychocardiology Unit, Cardiovascular Prevention and Rehabilitation, Swiss Cardiovascular Center, University Hospital Berne, Berne, Switzerland (R.v.K.).

View larger version (9K): [in this window] [in a new window]   Figure 1. (A–C) The stressor elicited a significant increase in mean ± standard error of mean of catecholamines and of D-dimer across all time points assessed (all p values <.001).

View larger version (14K): [in this window] [in a new window]   Figure 2. (A) Significant relationships between "total stress" and D-dimer total area under the curve (AUC) across all time points (omnibus test). (B–D) Significant relationships between "challenge" and D-dimer measures for the three time intervals. D-dimer values are expressed as arbitrary AUC units, which, moreover, were normalized for (A and B) D-dimer total AUC and (D) D-dimer recovery AUC.