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Cardiac-related Hospitalization and/or Death Associated With Immune Dysregulation and Symptoms of Depression in Heart Failure Patients

From the Department of Medicine (L.S.R., A.M.) and Department of Psychiatry (P.J.M., S.H., T.R., V.R.), University of California, San Diego; and Department of Psychiatry and Biobehavioral Sciences and Neuropsychiatric Institute and Cousins Center for Psychoneuroimmunonology (M.R.I.), University of California, Los Angeles.

View larger version (8K): [in this window] [in a new window]   Figure 1. Relationship between IFN-gamma/IL-10 ratios and Hamilton Depression Scores in those with and without incidence of cardiac related rehospitalization and/or death.

View larger version (8K): [in this window] [in a new window]   Figure 2. Relationship between Hamilton Depression Scores and distance covered in the six minute walk task.

View larger version (14K): [in this window] [in a new window]   Figure 3. Significant baseline differences in Hamilton Depression Scores between those who later had an incidence of cardiac related rehospitalization and/or death and those who did not, * p < .05. Error bars represent standard error of the mean.

View larger version (13K): [in this window] [in a new window]   Figure 4. Significant baseline differences in IFN-gamma/IL-10 ratios between those who later had an incidence of cardiac related rehospitalization and/or death and those who did not, * p = .05. Error bars represent standard error of the mean.